Aniba canelilla (Kunth) Mez (Lauraceae): A Review of Ethnobotany, Phytochemical, Antioxidant, Anti-Inflammatory, Cardiovascular, and Neurological Properties
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Aniba canelilla (Kunth) Mez (Lauraceae): A Review of Ethnobotany, Phytochemical, Antioxidant, Anti-Inflammatory, Cardiovascular, and Neurological Properties
Aniba canelilla (Kunth) Mez, known as the “Casca preciosa” (bark valuable), falsa canela (cinnamon flavored) Casca-do-maranhão (skin maranhão), and Folha-preciosa (leaves precious) is a species of aromatics from family Lauraceae, is widely distributed in the Amazon region.
In folk medicine, is indicated for the treatment of a large variety of ailments, including digestive, respiratory, inflam] matory, painful, and disorders of the central nervous system, it is provided mainly in the form of tea or decoction orally. The essential oil is referred to as natural antioxidants for food preservation and control of the disease, shows great potential for use in cosmetics, fragrances, and pharmaceutical products sector.
This review aims to critically and comprehensively discuss the characteristics of ethnobotany, phytochemical constitution, and scientifically tested biological properties A. canelilla, systematization of knowledge about species and propose new perspectives for research and development. The chemical composition A. canelilla including 1-nitro-2-phenylethane, metyleugenol, eugenol, safrole, anabasin, anbin, tannins, α-pinene, b-pinene, b-felandren, b-caryophyllene, b-sesquifelandren, p-cymene, linalool, α-copaene, and spatulenol.
Research by the ethanol extract, essential oils, and the main constituent (1-nitro-2-phenylethane and metyleugenol) have revealed the antioxidant, antinociceptive, anti-inflammatory, cardio-modulation, hypotension (vasorelaxant), hypnotic, anxiolytic, anticholinesterase, and antibiotic properties (trypanomicidal, leishmanicidal, and antifungal). Some of these effects are potentially useful for the treatment of diseases related to aging, such as cardio and cerebrovascular, chronic inflammation, neurological and degenerative diseases. However, it is necessary to advance in the clinical use of research and development of therapeutic products.
Aniba canelilla (Kunth) Mez (Lauraceae): A Review of Ethnobotany, Phytochemical, Antioxidant, Anti-Inflammatory, Cardiovascular, and Neurological Properties
Ethnobotany Phytochemical and Pharmacological Activity Kigelia africana (Lam.) Benth. (Bignoniaceae)
Kigelia africana have been used in the management of human disease since time immemorial. Ethnobotanists have documented traditional use K. africana, which includes treatment of skin disorders, cancer and gynecological complaints, among others. It has interested scientists, who have researched K. africana plant parts for their bioactivity. This review provides a deep understanding of ethnobotany, phytochemistry and pharmacology of K. africana.
Web search engine Google and Google Scholar, as well as databases of PubMed, Scopus, JSTOR, HINARI, SID, Ajol and Springer Link, deep searched using key words and phrases. institutional reports and conference papers are also consulted. A total of 125 sources of relevant international literature met the inclusion criteria were included. Kigelia africana have biologically active phytochemicals, many of which have been isolated. While fruits are most often cited in pharmacological studies, other plant parts are also used in herbal preparations.
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Description: DescriptionFor research use only. Not to be used for diagnostic purposes.Intact Genomics COVID-19 or SARS-CoV-2 Coronavirus detection kit is used for in vitro detection of SARS-CoV-2 using Real-Time quantitative PCR (RT-qPCR). The coronavirus SARS-CoV-2 was announced as the etiological agent of cases of pneumonia outbreak. This Coronavirus detection kit allows efficient cDNA synthesis and qPCR in a single tube. This probe based one step RTqPCR 2x master mix contains Reverse Transcriptase, Taq DNA polymerase, RNase inhibitor, MgCl2, dNTPs, stabilizers and low ROX reference dye with proprietary buffer providing improved RT-qPCR efficiency, wider dynamic range, superior sensitivity and specificity. In addition, the kit contains CDC recommended primers/ probe sets. This kit can be used to detect SARS-CoV-2 in respiratory specimens such as sputum, nasopharyngeal, oropharyngeal aspirates, washes or swabs and tracheal aspirates.IgScript™ Reverse Transcriptase is a recombinant MMLV reverse transcriptase with reduced RNase H activity, increased thermostability and can produce cDNA from small amount of total RNA for real-time RT-qPCR analysis and other applications. Taq DNA Polymerase is a thermostable DNA polymerase that possesses a 5´→3´ polymerase (1, 2) and a 5´→3´ exonuclease activity (3, 4). The amplification step features a high quality Taq DNA Polymerase which offers robust, reliable and better amplification.Product Includes:RT-qPCR 2x master mixCDC recommended primer/probe setsCOVID-19 positive control (PTC)
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Description: IDO1 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO1 Inhibitor Screening Assay Kit (BPS Cat. #72021) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).
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Description: TDO Fluorogenic Reaction Solution is an optimized, proprietary_x000D_formulation containing all the necessary reaction components for TDO-catalyzed_x000D_conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays._x000D_This product is intended to be used with the BPS Human TDO Fluorogenic Inhibitor_x000D_Screening Assay Kits (BPS Cat. #72039 & Cat. #72049) and/or with purified, active TDO,_x000D_His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).
Description: IDO1 Fluorogenic Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (BPS Cat. #72037 &Cat. #72047) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).
Commercially available products have been formulated from K. africana, although many have not been fully standardized. Despite numerous attempts by researchers to scientifically validate the use of traditional K. africana, many remain simply claims, so the need to do more research, more traditional use of scientific validation, new bioactive phytochemical isolates and standardization K. africana products.