Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae)

Ethnopharmacological relevance: The genus Bulbine (Asphodelaceae) is spread in South Africa and Australia and has been traditionally used for a variety of medicinal applications such as treating skin diseases, burns, diarrhea, and sexually transmitted diseases.


The purpose of this review:
The aim is to present a critical review of important species of the genus Bulbine ethnomedicinally with a comprehensive overview of the chemical content and biological activity.


Materials and methods: This article is an overview of published literature on the genus Bulbine in six decades with regard to the composition of phytochemical and pharmacological potential of each with the help of the data obtained from the search engine Google Scholar search string is done using key words to get relevant publications of scientific databases including ACS Journals, PubMed, Science Direct, SciELO, Sci Finder, Springer, Tailor & Francis, the Plant List database, web of Science and Wiley.


Results: The literature survey revealed that only 12 species in the genus Bulbine has been reported to be used by traditional scientific record Anthraquinones ethnomedicinal use emerged as the most abundant phytochemicals in the genus. metabolite isolated / detected more including isofuranonaphthoquinones, flavonoids and triterpenoids. Promising pharmacological activity has been reported by members of the genus by antiplasmodial, antitrypanosomal, antiviral, antioxidant, anticancer, anti-inflammatory activity and anti-microbial, a powerful wound healing properties and to improve reproduction.


Conclusion: This review shows the traditional use of this genus and preventive and curative properties in the management of diseases listed support of bioassay test compounds and extracts. State-of-the-art analytical techniques required for the characterization and quantification of compounds in the genus. The efficacy of the therapeutic potential of the species Bulbine requires further confirmation with pre-clinical studies and clinical.

 Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae)
Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae)

Ethnobotany and Antimicrobial Peptides From Plants Family Solanaceae: An Update and Future Prospects

Solanaceae is an important plant families that have played an important role in traditional medicine and human nutrition. Rich in bioactive metabolites Solanaceae members and has been used by different tribes around the world for centuries. antimicrobial peptides (AMP) of the plant have attracted great interest in recent years and raised new hope for developing new antimicrobial agents to face the challenges of antibiotic resistance.

This review aims to summarize the AMP reported from plants of the Solanaceae with the possible molecular mechanisms of action and correlate them with the traditional use of antimicrobial action of peptides reported. A systematic literature review conducted by using a different database until August 2019 based on inclusion and exclusion criteria. According to the literature, various AMP including defensins, protease inhibitors, lectins, thionin-like peptides, vicilin-like peptides, and snaking isolated from plants of the Solanaceae and involved in their defense mechanism.

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Faecalibacterium prausnitzii RT PCR kit

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This peptide shows activity of antibacterial, antifungal and antiviral significantly to both plants and organisms to the human host. Brugmansia, Capsicum, Datura, Nicotiana, Salpichora, Solanum, Petunia, and Withania is the most studied genera for AMP. Among this genus, Capsicum and Solanum top ranked according to the total number of studies (35% -38% of study) for different AMP.