Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae)
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Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae)
Ethnopharmacological relevance: The genus Bulbine (Asphodelaceae) is spread in South Africa and Australia and has been traditionally used for a variety of medicinal applications such as treating skin diseases, burns, diarrhea, and sexually transmitted diseases.
The purpose of this review: The aim is to present a critical review of important species of the genus Bulbine ethnomedicinally with a comprehensive overview of the chemical content and biological activity.
Materials and methods: This article is an overview of published literature on the genus Bulbine in six decades with regard to the composition of phytochemical and pharmacological potential of each with the help of the data obtained from the search engine Google Scholar search string is done using key words to get relevant publications of scientific databases including ACS Journals, PubMed, Science Direct, SciELO, Sci Finder, Springer, Tailor & Francis, the Plant List database, web of Science and Wiley.
Results: The literature survey revealed that only 12 species in the genus Bulbine has been reported to be used by traditional scientific record Anthraquinones ethnomedicinal use emerged as the most abundant phytochemicals in the genus. metabolite isolated / detected more including isofuranonaphthoquinones, flavonoids and triterpenoids. Promising pharmacological activity has been reported by members of the genus by antiplasmodial, antitrypanosomal, antiviral, antioxidant, anticancer, anti-inflammatory activity and anti-microbial, a powerful wound healing properties and to improve reproduction.
Conclusion: This review shows the traditional use of this genus and preventive and curative properties in the management of diseases listed support of bioassay test compounds and extracts. State-of-the-art analytical techniques required for the characterization and quantification of compounds in the genus. The efficacy of the therapeutic potential of the species Bulbine requires further confirmation with pre-clinical studies and clinical.
Ethnobotany, phytochemistry and pharmacological significance of the genus Bulbine (Asphodelaceae)
Ethnobotany and Antimicrobial Peptides From Plants Family Solanaceae: An Update and Future Prospects
Solanaceae is an important plant families that have played an important role in traditional medicine and human nutrition. Rich in bioactive metabolites Solanaceae members and has been used by different tribes around the world for centuries. antimicrobial peptides (AMP) of the plant have attracted great interest in recent years and raised new hope for developing new antimicrobial agents to face the challenges of antibiotic resistance.
This review aims to summarize the AMP reported from plants of the Solanaceae with the possible molecular mechanisms of action and correlate them with the traditional use of antimicrobial action of peptides reported. A systematic literature review conducted by using a different database until August 2019 based on inclusion and exclusion criteria. According to the literature, various AMP including defensins, protease inhibitors, lectins, thionin-like peptides, vicilin-like peptides, and snaking isolated from plants of the Solanaceae and involved in their defense mechanism.
48 reaction RT premix with nanoscript 2, 48 reactions
Description: DescriptionFor research use only. Not to be used for diagnostic purposes.Intact Genomics COVID-19 or SARS-CoV-2 Coronavirus detection kit is used for in vitro detection of SARS-CoV-2 using Real-Time quantitative PCR (RT-qPCR). The coronavirus SARS-CoV-2 was announced as the etiological agent of cases of pneumonia outbreak. This Coronavirus detection kit allows efficient cDNA synthesis and qPCR in a single tube. This probe based one step RTqPCR 2x master mix contains Reverse Transcriptase, Taq DNA polymerase, RNase inhibitor, MgCl2, dNTPs, stabilizers and low ROX reference dye with proprietary buffer providing improved RT-qPCR efficiency, wider dynamic range, superior sensitivity and specificity. In addition, the kit contains CDC recommended primers/ probe sets. This kit can be used to detect SARS-CoV-2 in respiratory specimens such as sputum, nasopharyngeal, oropharyngeal aspirates, washes or swabs and tracheal aspirates.IgScript™ Reverse Transcriptase is a recombinant MMLV reverse transcriptase with reduced RNase H activity, increased thermostability and can produce cDNA from small amount of total RNA for real-time RT-qPCR analysis and other applications. Taq DNA Polymerase is a thermostable DNA polymerase that possesses a 5´→3´ polymerase (1, 2) and a 5´→3´ exonuclease activity (3, 4). The amplification step features a high quality Taq DNA Polymerase which offers robust, reliable and better amplification.Product Includes:RT-qPCR 2x master mixCDC recommended primer/probe setsCOVID-19 positive control (PTC)
Description: TDO Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for TDO-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS TDO Inhibitor Screening Assay Kit (BPS Cat. #72023) and/or with purified, active TDO, His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).
Description: IDO1 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO1 Inhibitor Screening Assay Kit (BPS Cat. #72021) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).
Description: IDO2 Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO2-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS IDO2 Inhibitor Screening Assay Kit (BPS Cat. #72022) and/or with purified, active IDO2, His-tag (BPS Cat. #71194) in combination with 1x IDO2 Assay Buffer (BPS Cat. #73004).
amfiSure 1-Step RT-qPCR Premix, No Rox, 25ul reaction, 8-stip tube
Description: TDO Fluorogenic Reaction Solution is an optimized, proprietary_x000D_formulation containing all the necessary reaction components for TDO-catalyzed_x000D_conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays._x000D_This product is intended to be used with the BPS Human TDO Fluorogenic Inhibitor_x000D_Screening Assay Kits (BPS Cat. #72039 & Cat. #72049) and/or with purified, active TDO,_x000D_His-tag (BPS Cat. #71195) in combination with 1x TDO Assay Buffer (BPS Cat. #73006).
Description: IDO1 Fluorogenic Reaction Solution is an optimized, proprietary formulation containing all the necessary reaction components for IDO1-catalyzed conversion of L-tryptophan (L-Trp) to kynurenine (Kyn) in in vitro enzyme activity assays. This product is intended to be used with the BPS Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (BPS Cat. #72037 &Cat. #72047) and/or with purified, active IDO1, His-tag (BPS Cat. #71182) in combination with 1x IDO1 Assay Buffer (BPS Cat. #73002).
This peptide shows activity of antibacterial, antifungal and antiviral significantly to both plants and organisms to the human host. Brugmansia, Capsicum, Datura, Nicotiana, Salpichora, Solanum, Petunia, and Withania is the most studied genera for AMP. Among this genus, Capsicum and Solanum top ranked according to the total number of studies (35% -38% of study) for different AMP.
